| Available Subtitles: Spanish Available Audio Tracks: English (Dolby Digital 2.0 Surround), Spanish (Dolby Digital 2.0 Surround), French (Dolby Digital 2.0 Surround) |
| Robert De Niro | Leonard Lowe | | Robin Williams | Dr. Malcolm Sayer | | Penelope Ann Miller | Paula | | Judith Malina | Rose | | Julie Kavner | Eleanor Costello | | John Heard | Dr. Kaufman | | Barton Heyman | Bert | | Anne Meara | Miriam | | Laura Esterman | Lolly | | Jayne Haynes | Frances | | Yusef Bulos | Joseph | | Gloria Harper | Dottie | | Mary Catherine Wright | Nurse Beth | | Keith Diamond | Anthony | | Tiger Haynes | Janitor | | Bradley Whitford | Dr. Tyler | | Harvey Miller | Hospital Director | | Peter Stormare | Neurochemist | | Waheedah Ahmad | Hysterical Woman | | Christina Huertes | Christina | | Judy Jacksina | Hospital Receptionist | | Rico Elias | Orderly #1 | | Chris Carolan | EEG Technician | | Max Rabinowitz | Ward #5 Orderly | | Byron Utley | Ward #5 Patient #2 | | Paul Montgomery | Ward #5 Patient #4 | | Vincent Pastore | Ward #5 Patient #6 | | Libby Titus | Club Singer | | Tomislav Novakovic | Bartender | | Anthony J. Nici | Young Leonard | | Buck Smith | Leonard's Friend #2 | | Vin Diesel | Hospital Orderly | | Jan Saint | Man hit with ball | | Ruth Nelson | Mrs. Lowe | | Alice Drummond | Lucy | | George Martin | Frank | | Richard Libertini | Sidney | | Dexter Gordon | Rolando | | Le Clanch?? du Rand | Magda | | Steven Randazzo | Luis | | Gwyllum Evans | Desmond | | Mary Alice | Nurse Margaret | | Steve Vinovich | Ray | | John Christopher Jones | Dr. Sullivan | | Max von Sydow | Dr. Peter Ingham | | Tanya Berezin | Psychiatrist | | Shane Fistell | Man in Hall | | Charles Keating | Mr. Kean | | Linda Burns | Fishsticks | | Gary Tacon | George, Security Guard | | Mel Gorham | Nurse Sara | | Debra Kovner-Zaks | Cafeteria Nurse | | Gordon Joseph Weiss | Ward #5 Patient | | Anthony McGowen | Ward #5 Patient #3 | | Leonard Tepper | Ward #5 Patient #5 | | Howard Feller | Ward #5 Patient #7 | | Michael Hyde | Bus Driver | | Adam Bryant | Librarian | | Oliver Block | Leonard's Friend #1 | | Joan E. MacIntosh | Teacher |
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